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Similar to a stabilization of a segment with idiopathic disc degeneration using a dynamic posterior implant where a recovery of the nucleus signal can be observed in some cases, 5 it has also been shown that, after posteriorly stabilized burst fractures, the nucleus signal may be retained even after implant removal

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The detoxification reactions comprise the first four steps of mercapturic acid synthesis, [19] with the conjugation to GSH serving to make the substrates more soluble and allowing them to be removed from the cell by transporters such as multidrug resistance-associated protein 1 (MRP1)

Probenecid is not effective if a patient has kidney dysfunction [creatinine greater than 2.0 (creatinine is a measure of a waste product excreted by the kidney)